儿童阻塞性睡眠呼吸暂停低通气综合征与常见炎症因子及相关疾病的关系

摘要

儿童阻塞性睡眠呼吸暂停低通气综合征(OSAHS)最主要的发病原因是扁桃体、腺样体肥大(AH),可影响儿童的生长发育.其发病机制与炎症有关.OSAHS患儿可发生全身及局部炎症反应,但相关机制尚未明确.本文回顾了近年来有关OSAHS及AH与多种细胞因子的研究,对儿童OSAHS与变应性鼻炎及分泌性中耳炎关系的研究结果进行了初步分析.%Tonsil and adenoid hypertrophy are the most important causes of pediatric obstructive sleep apnea hypopnea symptom (OSAHS),which could affect the growth of children.The pathogenesis of OSAHS is not clear.Some studies showed that it was associated with inflammation.OSAHS children might get systemic and local inflammation.This paper reviewed the research of OSAHS and adenoid hypertrophy with some common cytokines,and made a preliminary analysis on the relationship between OSAHS and allergic rhinitis and otitis media with effusion.