抗肿瘤药罗米地辛的药理与临床研究

摘要

Romidepsin is a potent histone deacetylase inhibitor, and is used in the treatment of cutaneous T-cell lymphoma (CTCL). A literature search was conducted using PUBMED with the key word romidepsin. The pharmacological effects, pharmacokinetics, clinical research, safety and drug interactions of romidepsin were reviewed in this paper.%抗肿瘤药罗米地辛是一种有效的组蛋白去乙酰化酶抑制剂,临床上用于治疗皮肤T细胞淋巴瘤.文中通过PUBMED对罗米地辛进行文献检索,并对其药理作用、药动学、临床研究、安全性及药物的相互作用等进行了综述.