头孢哌酮钠舒巴坦钠联合左氧氟沙星治疗医院获得性肺炎的临床疗效观察

摘要

Objective To investigate the clinical efficacy and adverse reactions of the cefoperazone sulbac -tam combined with levofloxacin in the treatment of hospital acquired pneumonia ( HAP) .Methods Forty-two patients with HAP were randomly divided into treatment group and control group , each group with 21 patients.The treatment group was treated with cefoperazone sulbactam combined with levofloxacin and control group was treated with cefopera -zone sulbactam , treatment course was 7~8 d.Results The time of symptoms and sign returned to normal in the treatment group was (48.24 ±7.54)h, that in the control group was (72.36 ±10.24)h (P<0.01);the clinical ef-ficacy of the treatment group was better than the control group ( P<0.05 ) , incidence of adverse reactions was not sta-tistically significant between the two groups ( P>0.05 ) .Conclusion The efficacy of cefoperazone sulbactam com-bined with levofloxacin in the treatment of HAP is significantly better than cefoperazone sulbactam , and this combined use is worthy of promotion .%目的：探讨头孢哌酮钠舒巴坦钠联合左氧氟沙星治疗医院获得性肺炎（ hospital acquired pneu-monia，HAP）的临床疗效和不良反应。方法将42例HAP确诊病例随机分为治疗组和对照组，每组21例。治疗组用头孢哌酮钠舒巴坦钠联合左氧氟沙星治疗，对照组用头孢哌酮钠舒巴坦钠治疗，疗程均为7～8d。结果治疗组症状、体征恢复正常的时间为（48.24±7.54）h，对照组为（72.36±10.24）h，两组比较差异有统计学意义（P＜0.01）；治疗组的临床疗效优于对照组（P＜0.05）；两组不良反应发生率比较差异无统计学意义（ P＞0.05）。结论头孢哌酮钠舒巴坦钠联合左氧氟沙星治疗HAP的疗效明显优于单用头孢哌酮钠舒巴坦钠，值得临床推广应用。