经蝶窦入路垂体腺瘤手术并发症分析

摘要

Objective To analyze the complications of transsphenoidal operation for pituitary adenomas.Method Postoperative complications of 323 patients underwent transphenoidal surgery for pituitary adenoma between January 2001 and December 2009 in our department were retrospectively reviewed.Results Insipidus was the most common complication after the operation with the incidence of 52％.The other complications were visual deterioration( 2％), cerebrospinal fluid rhinorrhea( 6％),intracranial infection ( 3％), pituitary insufficiency( 2.4％), pituitary articulo ( 0.6％).Conclusions Better understanding of the indications for transsphenoidal surgery and familiarity with the regional anatomy should further lower the rates of death and complications.Skill surgical technique and clinical experience are also very important to improve the therapeutic efficacy.%目的 分析单鼻孔蝶窦入路并结合神经内镜切除垂体腺瘤的手术并发症.方法 回顾性分析经蝶窦切除垂体腺瘤323例患者的术后并发症.结果 本组尿崩症病例发生率为52%,脑脊液漏19例(6%),迟发2例,2例行手术修补.颅内感染发生率3%(11例),其中1例因感染反复发作死亡.垂体功能低下8例,有2例患者因为感染和饮食不佳出现垂体危象,视力减退发生率2%(6例).结论 熟悉手术局部解剖,把握手术适应证,熟练掌握手术技能、不断总结临床实践经验,才能降低手术并发症和病死率,提高治疗效果.