奠基者基因的进化年龄及其意义

摘要

宏演化的趋势之一是生物由简单到复杂.传统上,这是古生物学、比较形态学和进化-发育探讨的主题.随着基因组数据的不断积累,当今一支以基因组进化年龄层分析为主要研究方法的新军加入了进来.基因组进化年龄层就是在系统发育层面上新出现一组共同起源的奠基者基因.本文将介绍这支新军及其在个体发育和肿瘤研究上发挥的作用.%Traditionally, the macroevolutionary trends were explored by paleobiology, comparative morphology and evodcvo approaches. Recently. Genomic phylostratigraphy, a new approach, has appeared on these trends, with the cumulative increase of genomic data. It can contribute to analyses for phylotypic stage in the relationship between phylogeny and ontogeny, as well as cancer studies. The paper presents the core of phylostratigraphy and its significance for ontogeny and cancer research.