目的 探讨保留迷走神经腹腔支胃癌根治术的临床应用价值.方法 128例胃癌病例随机分为两组,各64例,分别实行保留迷走神经腹腔支胃癌根治术(观察组)和传统胃癌根治术(对照组),并进行胃肠动力学和胃肠激素分泌水平的对比.结果 观察组在术后首次排气时间、首次排便时间优于对照组(P<0.05),而淋巴结清扫个数与对照组无明显区别(P>0.05).观察组血清胃泌素和基础胃酸分泌量明显低于对照组(P=0.001或P<0.05),而空腹血浆胰多肽水平明显高于对照组(P<0.05).空腹血清胰岛素水平两组无明显差异(P>0.05).结论 保留迷走神经腹腔支的胃癌根治术能加快病人胃肠道功能的恢复和更好的营养吸收.%Objective To explore the clinical value of celiac branch of vagus nerve-preserving radical gastrectomy. Methods A total of 128 gastric cancer patients were randomly divided into observation group ( n =64) receiving celiac branch of vagus nerve-preserving radical gastrectomy and control group ( n =64) receiving traditional classic radical resection. The two groups were compared gastro-intestinal dynamics and hormone levels. Results The first exhaust time and the first bowel movement were better in the observation group than the control group (P ＜0.05), while the number of lymph node dissection had no significant difference (P ＞0. 05).The basis levels of observed serum gastrin and gastric acid secretion were significantly lower in the observation group than those in the control group ( P ＜ 0. 05 ). There was no significant difference of the fasting serum insulin levels (P ＞0.05). The fasting plasma pancreatic polypeptide levels was significantly higher in the observation group than thecontrolgroup(P＜0.05). Conclusion Abdominal vagus nerve branch retention of the radical surgery for gastric cancer patients can accelerate the recovery of gastrointestinal function and get better nutrient absorption.
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