Objective To evaluate the clinical value and therapeutic effect of selective hepatic artery embolization with Pingyangmycin-lipiodol emulsion ( PLE ) in the treatment for huge hepatic hemangioma. Methods 35 patients with huge hepatic hemangioma were treated with PLE by selective hepatic artery embolization and sclerosis. The size of tumors was measured and compared before and after the embolotherapy, the clinical symptoms and complications were observed. Results After the embolotherapy, the size of tumors was decreased evidently. By the end of the the third, the sixth, the nineth, and the twelfth month, there was an average shrinkage of 26. 6% , 41. 5% ,58. 3% and 68. 7% in the size of tumors retrospectively. After the embolotherapy , CT indicated the huge hepatic hemangioma disappeared entirely in 4 cases at the end of the twelfth and the eighteenth month. The clinical symptoms were alleviated or recovered completely. No severe complications occurred. Conclusion It is suggested that selective hepatic artery embolization with Pingyangmycin-lipiodol emulsion is safe and effective with fewer complications on huge hepatic hemangioma.%目的 评价平阳霉素碘油乳剂经选择性肝动脉栓塞治疗巨大肝海绵状血管瘤的临床应用及疗效.方法 对35例有症状的巨大肝海绵状血管瘤患者采用Seldinger技术,经皮股动脉穿刺行肝动脉插管注入平阳霉素碘化油乳剂栓塞硬化肝血管瘤,并用明胶海绵颗粒栓塞瘤体供血动脉.栓塞术后定期随访观察血管瘤缩小、临床症状缓解及并发症情况.结果 栓塞治疗后肿瘤进行性缩小,术后第3、6、9、12个月复查,肿瘤平均缩小程度分别为26.6％、41.5％、58.3％、68.7％；其中5例肝血管瘤分别于第12个月和第18个月复查CT提示血管瘤瘤体基本消失；所有患者临床症状明显减轻或消失,无严重并发症发生.结论 平阳霉素碘油乳剂栓塞治疗肝海绵状血管瘤安全有效、并发症少,具有重要的临床应用价值.
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