ICU机械通气患者镇静效果观察与护理

摘要

Objective To explore the sedative effect of propofol, midazolam for ICU patients with mechanical ventilation and the nursing experience.Methods Totals of 120 patients of ICU from June 2012 to December 2012 were randomly selected and divided into experiment group ( n =60 ) and control group ( n=60), experiment group were given propofol injection sedation, control group were given midazolam sedation, using Ramsay sedation score, compared two groups of patients the onset time of drug, recovery time after stopping drug, medicine adverse reaction and vital signs changes.Results In experiment group, the onset time was (23 ±8)s, the recovery time is (22 ±6)min, patients in control group were (48 ±9)s, (58 ±12)mins, and the differences between two groups were statistically significant (t =3.12,5.67,respectively;P<0.05).After sedation, heart rate (74 ±11) times/min, and breath (15 ±3) times/min of experiment group were slower than that of control group, and the difference was statistically significant (P<0.05).Conclusions Propofol sedation effect is good, and can fast acting, while it has a great influencing on the heart rate.%目的：探讨丙泊酚、咪达唑仑应用于机械通气患者镇静的疗效及护理体会。方法随机选择ICU机械通气患者120例，采用随机数字表法分为试验组与对照组，每组60例，试验组给予丙泊酚注射液镇静，对照组给予咪达唑仑镇静，采用Ramsay镇静评分比较两组患者用药后起效时间及停药后苏醒时间，比较两组用药后不良反应及生命体征变化。结果试验组患者起效时间、苏醒时间分别为（23±8）s，（22±6）min，对照组患者分别为（48±9）s，（58±12）min，两组比较差异有统计学意义（t值分别为3．12，5．67；P＜0．05）。试验组患者镇静后心率（74±11）次／min，呼吸（15±3）次／min，较对照组出现减慢现象，差异有统计学意义（t值分别为－5．28，－4．17；P＜0．05）。结论丙泊酚镇静效果好，起效快，但对心率影响较大。