Objective To investigate curative effect by modified oral administration of Shaofu Zhuyu decoction combined with external application of self-made Huayu Xiaotong powder in the treatment of primary dysmenorrhea. Methods A total of 120 patients with primary dysmenorrhea of cold-coagulation and blood-stasis type were randomly divided into observation group and control group, with 60 cases in each group. The observation group received oral administration of Shaofu Zhuyu decoction combined with external application of self-made Huayu Xiaotong powder, and the control group received oral administration of indometacin, Yueyueshu and fenbid for treatment. Observation and comparison were made on curative effect, symptom relief time and cure time between the two groups. Results The observation group had obviously higher total effective rate as 96.67% than 68.33% in the control group, and the difference had statistical significance (P<0.05). The observation group had shorter symptom relief time and cure time than the control group, and their difference had statistical significance (P<0.05). Conclusion Modified oral administration of Shaofu Zhuyu decoction combined with external application of self-made Huayu Xiaotong powder shows precisely curative effect in the treatment of primary dysmenorrhea, and this method is worth clinical promotion.%目的：探讨少腹逐瘀汤加减内服配合自制化瘀消痛散外敷在原发性痛经治疗中的疗效。方法120例寒凝血瘀型原发性痛经患者，随机分为观察组和对照组，各60例。观察组患者口服少腹逐瘀汤配合自制化瘀消痛散外敷，对照组患者口服消炎痛、月月舒和芬必得等药物治疗，观察并比较两组患者治疗效果及症状缓解与治愈时间。结果观察组患者治疗总有效率为96.67%，显著高于对照组的68.33%，差异具有统计学意义(P<0.05)；观察组患者症状缓解与治愈时间短于对照组，差异具有统计学意义(P<0.05)。结论少腹逐瘀汤加减内服配合自制化瘀消痛散外敷治疗原发性痛经疗效显著，值得临床推广。
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