单侧额下入路显微手术切除大型跨中线嗅沟脑膜瘤的临床分析

摘要

Objective To investigate the efficacy and safety of surgical treatment for large olfactory groove meningiomas via a unilateral subfrontal approach.Methods The clinical data of 18 patients with large olfactory groove meningiomas were analyzed retrospectively.The largest diameter of the tumor was 4.2-6.6 cm.The microsurgery was performed via the unilateral subfrontal approach.Results The tumor resection was Simpson grade Ⅰ in 4 cases,grade Ⅱ in 13 and grade Ⅲ in 1.There was no death.Cerebrospinal fluid leakage and intracranial infection was observed in 1 case,who recovered well after treatment.All patients were followed up for 6-36 months with a mean period of 14.9 months,and recovered well without recurrence.Conclusion Unilateral subfrontal approach is a safe and effective approach for the treatment of large olfactory groove meningiomas.%目的 探讨经单侧额下入路切除大型跨中线嗅沟脑膜瘤的安全性与有效性.方法 回顾性分析18例大型嗅沟脑膜瘤病例资料,肿瘤最大径4.2～6.6 cm,均经单侧额下入路进行显微手术.结果 肿瘤切除达Simpson Ⅰ级4例,Ⅱ级13例,Ⅲ级1例.无手术死亡病例,1例术后出现脑脊液漏合并颅内感染,治疗后康复出院.术后随访6～36个月,平均14.9个月,均恢复良好,未见肿瘤复发.结论 单侧额下入路治疗大型跨中线嗅沟脑膜瘤是合理手术方式,可取得满意手术切除程度和良好疗效.