四维超声时间-空间关联成像对孕期胎儿室间隔缺损诊断的临床价值

摘要

Objective To explore the clinical value of four-dimensional ultrasound spatio-temporal correlation image (STIC) in the identification of the diagnosis room septal defect (VSD) in prenatal.Method Selected Court Ultrasound 2011 to 2015 by the two-dimensional ultrasound screening technology and STIC get 38 cases of fetal VSD were retrospectively analyzed to or after the final autopsy results or postnatal follow-up results as the gold standard to calculate two STIC-dimensional ultrasound and clinical diagnostic value of the VSD.Result STIC sample inspection time for each case, each image to obtain the required time were significantly shorter than the two-dimensional ultrasound (P<0.05); 36 patients were diagnosed VSD fetuses, STIC correctly diagnosed 35 cases, one case of missed diagnosis, misdiagnosis does not appear case; correct dimensional ultrasound fetal diagnosis VSD in 28 cases, 8 cases of missed diagnosis, one case of misdiagnosis; calculated according to table 2 to give STIC fetal diagnosis VSD sensitivity of 97.22%, specificity of 100%, misdiagnosis rate was 2.78%, misdiagnosis rate 0.00%; two-dimensional ultrasound diagnosis of fetal VSD sensitivity of 77.78% and a specificity of 50.00%, 22.22% rate of missed diagnosis, misdiagnosis rate was 50.00%.ConclusionPrenatal screening for VSD application STIC technology has the advantages of fast and accurate.%目的探讨四维超声时间-空间关联成像（spatio-temporal image correlation，STIC）技术在产前胎检中鉴别诊断室间隔缺损（ventricular septal defect，VSD）的临床价值。方法选取本院超声科2011年3月至2015年4月经二维超声和STIC技术筛查得到的38例VSD胎儿资料进行回顾性分析，以最终引产后尸体解剖结果或出生后随访结果作为金标准，分析二维超声和STIC诊断VSD的临床价值。结果 STIC对每例样本检查时间、获取每幅图像所需要时间均显著短于二维超声（P＜0.05）；36例确诊VSD胎儿中，STIC正确诊断35例、漏诊1例，未出现误诊病例；二维超声正确诊断VSD胎儿28例、漏诊8例、误诊1例；STIC诊断VSD胎儿的灵敏度为97.22%、特异度为100%、漏诊率为2.78%、误诊率为0.00%；二维超声诊断VSD胎儿的灵敏度为77.78%、特异度为50.00%、漏诊率为22.22%、误诊率为50.00%。结论产前检查应用STIC技术筛查VSD具有快速准确的优点。