复方黄黛片联合全反式维甲酸治疗初发急性早幼粒细胞白血病的疗效

摘要

Objective: To observe the therapeutic efficacy of Compound Huangdai piece combined with all-trans retinoic acid (ATRA) on newly-diagnosed patients with acute promyelocytic leukemia (APL). Methods:22 cases of incipient APL patients were randomly divided into treatment group and control group, treatment group:ATRA 30 mg/d joint compound HuangDai tablet every 3~5 pieces, every day three times, ten days and to 30 tablet every day, oral;Control group:ATRA30mg/d, oral and As2O3 injection, intravenous drip. Observation for ease time and adverse drug reaction. Results:8 cases of ATRA joint compound HuangDai tablet treatment of 7 cases of patients with complete remission rate (CR) and long-term survival, 1 case is invalid. Conclusion:Compound Huangdai piece ATRA treatment of APL.%目的：观察复方黄黛片联合全反式维甲酸(ATRA)治疗急性早幼粒细胞白血病(APL)的疗效方法：22例初发APL患者随机分为治疗组、对照组,治疗组：ATRA 30mg/d联合复方黄黛片每天3~5片,每天3次,10天后加至30片每天,口服；对照组：ATRA30mg/d,口服与As2O3注射液,静脉滴注。观察持续缓解时间及药物不良反应。结果：8例ATRA联合复方黄黛片治疗患者7例完全缓解率(CR)并长期存活,1例无效。结论：复方黄黛片联合ATRA治疗APL疗效良好。