血清降钙素原变化率在指导重症细菌性肺炎疗效评估中的作用

摘要

目的：对血清降钙素原变化率在指导重症细菌性肺炎疗效进行探讨。方法：随机抽取25例重症细菌性肺炎患者，为观察组，另选取同时期我院治疗的轻症肺炎患者25例，为对照组，对两组患者在24h之内的血常规、体温、血清PCT、CRP水平等进行对比，分析两组患者的呼吸机使用例数、住院时间、抗生素使用情况以及死亡率。结果：观察组患者的CRP、血清PCT明显高于对照组（P＜0.05）。而两组患者在中性粒细胞百分比、WBC计数以及体温差异等方面差异不明显（P＞0.05）。PCT水平越高，重症肺炎患者越需要使用呼吸机进行辅助呼吸，患者的死亡率，抗生素使用与患者的住院时间相应增加。结论：在重症细菌性肺炎患者治疗中应用血清降钙素原，能够提高疾病的诊断有效率，具有一定的指导价值和评估作用，提高患者预后。%Objective: To investigate the rate of change of serum procalcitonin in guiding the efficacy of severe bacterial pneumonia explore. Methods: Ran domed 25 cases of severe bacterial pneumonia, As the observation group, Another selected 25 cases with mild pneumonia while in our hospital, As the control group, Two groups of patients within 24h of blood, body temperature, serum PCT, CRP level of contrast to the two groups of patients with ventilator number of cases, hospitalization, use of antibiotics, and mortality were analyzed. Results: The patients of CRP, serum PCT was significantly higher, there is a big difference, with statistical significance(P<0.05). The two groups of patients in terms of the percentage of neutrophils, WBC count, and no significant difference between the temperature differences do not have statistical significance(P>0.05). The higher PCT levels in patients with severe pneumonia need to use more ventilator-assisted breathing, increased mortality, length of stay and antibiotic use in patients will also be extended. Conclusion: Serum procalcitonin in patients with severe bacterial pneumonia treatment applications, can improve the efficiency of diagnosis of diseases, reflect the true condition of the patient, the diagnosis of severe bacterial pneumonia has a guiding value and assess the role of improve patient prognosis.