Monaco与Pinnacle治疗计划系统在食管癌放疗剂量验证上的比较

摘要

目的:比较分析Monaco与Pinnacle治疗计划系统在食管癌放疗剂量计算上的精确性.方法:选取食管癌病人16例,分别用Monaco与Pinnacle治疗计划系统做调强放疗计划及验证计划,然后用二维电离室矩阵Matrixx进行剂量数据的采集,接着比较分析误差阈值为2％/2 mm、3％/2 mm、3％/3 mm、5％/3 mm时的Gamma通过率.结果:在误差阈值下,Monaco治疗计划系统的剂量计算精确性高于Pinnacle治疗计划系统的剂量计算精确性,误差阈值为2％/2 mm、3％/2 mm和3％/3 mm时通过率分别高1.3％、1.1％和0.7％ (P＜0.05),误差阈值为5％/3 mm时无统计学意义(P＞0.05).结论:两套治疗计划系统的剂量计算精度均很高,均适用于临床,相比之下Monaco治疗计划系统要更高些,但其计算速度要明显慢于Pinnacle治疗计划系统.%Objective To compare and analyze the accuracy in dose calculation of Monaco and Pinnacle treatment planning systems (TPS) for the radiotherapy of esophageal cancer.Methods For 16 selected cases of esophageal cancer,intensitymodulated radiotherapy (IMRT) plan and verification plan were generated by Monaco and Pinnacle TPS,respectively.And then,the dose data were collected by using two-dimensional ion chamber array Matrixx.The Gamma passing rates with various error ranges of 2％/2 mm,3％/2 mm,3％/3 mm and 5％/3 mm were analyzed.Results The accuracy in dose calculation of Monaco TPS was higher than that of Pinnacle TPS within the error range,and the Gamma passing rate of Monaco TPS is 1.3％,1.1％ and 0.7％ higher according to the error ranges of 2％/2 mm,3％/2 mm and 3％/3 mm (P＜0.05 for all),respectively,while no significance was found at the criterion of 5％/3 mm (P＞0.05).Conclusion Both Monaco and Pinnacle TPS could offer clinically acceptable dose calculation accuracy.Compared with Pinnacle TPS,Monaco TPS has a higher accuracy in dose calculation but obviously slower calculation speed.