Objective To assess the value of MRI in fetal cerebral ventriculomegaly diagnosed by ultrasound and to evaluate the prognosis.Methods Totally 124 fetuses with cerebral ventriculomegaly or suspected with other neurological disea ses were examined by MRI,the diagnosis of MRI and ultrasound were compared.The outcome of pregnancy was followed up.Results Among the 124 fetuses,18 fetuses were diagnosed with ventriculomegaly combined with other neurological diseases by MRI,including 6 fetuses with suspected diagnosis by ultrasound,and 12 fetuses inconsistent with the results of ultrasound.The clinical outcome of 106 fetuses with isolated ventriculomegaly were followed up by MRh 11 fetuses were with termination of pregnancy,95 fetuses were with childbirth.Totally 45 infants was re examined by MRI and 9 cases of nervous system diseases were found among them.The incidence of nervous system diseases in the atrial width 12-15 mm group was higher than that of atrial width 10 ＜12 mm group (42.11 ％ vs 3.85％,P ＜0.01),the asymmetrical bilateral enlargement group was higher than that of symmetrical bilateral enlargement group (54.55％ vs 11.76％,P＜0.05);96.15％ (25/26) infants in the atrial width 10-＜12 mm were completely recovered to normal.Conclusion The effective combination of MRI and uhrasound can improve the rate o:f prenatal diagnosis.The fetus with the atrial width 10-＜ 12 mm has a good prognosis,while atrial width 12-15 mm and asymmetrical bilateral enlargement of the fetuses should pay attention to long-term follow-up after birth.%目的 探讨MRI对超声发现侧脑室增宽胎儿的诊断价值及出生后的预后评价.方法 选取超声发现胎儿侧脑室增宽或疑似合并其他神经系统疾病、接受产前MR检查的孕妇124例,比较MRI与超声的诊断结果并评估患儿出生后神经系统发育情况.结果 124例孕妇中,MRI诊断胎儿侧脑室增宽且合并其他神经系统疾病18例,包括确诊超声疑似诊断6例,诊断与超声结果不一致12例.MRI随访单纯性侧脑室增宽的106胎胎儿:11胎终止妊娠,95胎分娩.存活婴幼儿中45例复查头MRI,9例诊断为神经系统疾病,侧脑室宽度12～15 mm亚组发生率高于10～＜12 mm亚组(42.11％ vs 3.85％,P＜0.01),双侧脑室不对称增宽亚组高于对称性增宽亚组(54.55％ vs 11.76％,P＜0.05).侧脑室宽度10～＜12 mm亚组中96.15％(25/26)患儿出生后预后良好.结论 MRI与超声有效结合可以提高产前诊断率,单纯性侧脑室宽度10～＜12 mm的胎儿预后良好;对于12～15 mm及双侧脑室不对称增宽的胎儿,应重视出生后远期随访.
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