目的 观察采用Onyx胶栓塞治疗颅内动静脉畸形(CAVM)的效果.方法 应用Onyx胶栓塞治疗31例CAVM患者,评价治疗效果,并对21例患者术后随访3～18个月.结果 31例CAVM患者中,6例一次性栓塞畸形血管团>90%,其中畸形血管团完全消失4例,其余2例3个月内DSA复查畸形血管团完全消失;25例一次性栓塞≤90%,均接受多次栓塞或联合放射、手术治疗,其中单纯多次栓塞10例,多次栓塞后放射治疗7例、手术治疗8例.26例栓塞治疗后癫痫、头痛、头晕改善;3例术后出现头痛;2例并发颅内出血,其中1例左小脑动静脉畸形栓塞术后24 h出血,急诊手术治疗无效死亡.结论 Onyx胶用于血管内栓塞治疗CAVM疗效较好,是较为理想的血管内栓塞剂.%Objective To investigate the efficiency of Onyx embolization for treatment of cerebral arteriovenous malformation (CAVM). Methods Onyx embolization was performed for treatment of 31 patients of CAVMs. The efficiency was evaluated, and 21 patients were followed up for 3-18 months. Results Among all 31 patients, vascular malformations were embolized more than 90％ in 6 patients. CAVMs vanished in 4 patients after embolization, while DSA showed the malformations vanished in the other 2 patients within 3 months. Vascular malformations in 25 patients were embolized less than 90％, of which multiple embolizations alone was performed in 10 patients, post embolization surgery in 8 and irradiation in 7. Headache, swirl and epilepsy symptoms were improved in 26 patients after embolization. Three patients felt headache after surgery. Two patients followed with intracranial hemorrhage complications, and 1 of them died of bleeding 24 hours after embolization. Conclusion Onyx has good effect for endovascular embolization of CAVM and appears to be an ideal embolic material.
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