With the development of imaging technology and ultrasound contrast agents, ultrasound microbubbles are not only used for diagnosis, but also for therapy,Recently, more attention has been paid to use microbubbles as a new carrier of drug or gene. Meanwhile, ultrasound mediated microbubbles destruction can release the therapeutic drug or gene locally and suggest a certain advantage for target therapy. The application and development of ultrasound and microbubbles in liver carcinoma targeted therapy were reviewed in this article.%随着超声影像技术的不断发展和造影剂制备工艺的不断改进,超声造影剂正在从诊断领域向治疗领域拓展.作为一种新的药物和基因载体,造影剂受到广泛关注,同时其在增强超声介导疾病治疗方面也显示出一定优势.本文就造影剂联合超声辐照介导肝癌靶向治疗的研究进展进行综述.
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