Objective To investigate the imaging and clinicopathological characteristics of extrapleural solitary fibrous tumors (SFT). Methods The data of imaging findings and clinicopatholocal manifestations in 9 patients with surgically confirmed extrapleural SFT were analyzed retrospectively. Results There were 7 benign and 2 low grade malignant extrapleural SFT. All extrapleural SFT located in different parts of the body? Including 2 in the neck, 2 in the pelvic cavity, 2 in the abdomen, 1 in the leg, 1 in the orbit and 1 in the hip. Seven cases received CT scanning, on which the tumors presented as well-defined round or elliptic margins with clearly surrounding, and the size was from 31 mm×27 mm × 23 mm to 311 mm×170 mm×191 mm. The masses were heterogeneous, no lymph node metastasis was found. Four cases received MR imaging, and the small lesion was hypointense on T2WI and enhanced homogeneously after contrast injection. The capsule of tumor was seen in 7 cases, and the section of these tumors were ashen or sallow. The microscopic features included fusiformis, short fusiformis or orbicular-ovate, cytoplasm stained red and alternating hyper- and hypo-cellular areas. Im-munohistochemical staining showed all positive CD34 and Vim, while bcl-2 were positive in 6 patients and CD99 were positive in 7 patients, as well as S-100 and SMA were negative in 7 patients, Des were all positive. Conclusion CT is useful for judging the original site of the lesion and enhancement pattern. Hypointensity on T2WI with intense contrast enhancement is the distinctive manifestation of SFT. Combination imaging findings of CT and MRI can provide comprehensive information for diagnosis of these tumors. Final diagnosis relies on pathology.%目的 探讨胸膜外孤立性纤维性肿瘤(SFT)的影像学表现及临床、病理特征.方法 回顾性分析经病理证实的9例胸膜外SFT的影像学及临床、病理资料.结果 9例SFT中,7例为良性,2例为低度恶性；病变位于颈部2例,盆腔2例,腹部2例,下肢1例,眼眶1例,臀部1例.7例接受CT扫描,肿块多呈类圆形,边界较清晰,大小31 mm×27 mm×23 mm～311 mm×170 mm×191 mm；增强扫描后肿瘤明显强化,周围未见淋巴结转移.4例接受MR检查,小SFT的MRI较具特征性,T2WI呈等低信号,增强后均匀明显强化.病理:7例SFT有完整包膜,2例无明显包膜；镜下肿瘤细胞呈梭形、短梭形或卵圆形,胞浆红染,形成细胞密集区和疏松区；免疫组化:CD34和Vim均为阳性;bcl-2阳性6例,CD99阳性7例,S-100、SMA阴性7例,Des均为阴性.结论 CT能够清楚、准确显示SFT的病变范围、强化方式；T2WI呈低信号及增强后较明显强化是SFT较具特征性的MRI表现.联合应用CT和MR能为该病的诊断、治疗提供更全面的信息,最后诊断有赖于组织病理学检查.
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