耳穴贴压对轻中度原发性高血压干预效果的Meta分析

摘要

目的：采用 Meta分析系统评价耳穴贴压与西药调节轻、中度原发性高血压的临床疗效和安全性差异。方法全面检索耳穴贴压与西药比较治疗轻、中度原发性高血压的随机对照试验文献,选择合格研究并进行质量评价,采用RevMan5.3软件进Meta分析。结果共纳入14篇RCT文献,共1683例病人,但其方法学质量普遍不高。Meta分析结果,①降压疗效：单用耳穴贴压与单用西药比较,两组降压疗效差异无统计学意义；耳穴贴压+西药与单用西药比较,耳穴贴压+西药组明显优于单用西药组；②症状疗效：耳穴贴压+西药优于单用西药,纳入试验中未见不良反应报道。结论耳穴贴压治疗轻、中度原发性高血压是安全有效的。%Objective To evaluate the clinical efficacy and safety of auricular pressure therapy versus anti hypertensive western medicine for mild to moderate essential hypertension by meta analysis.Methods Randomized control ed trials (RCTs)of auricu-lar pressure therapy versus anti hypertensive western medicine in the treatment of mild to moderate essential hypertension were searched.Qualified researches were selected and evaluated.The RevMan4.2 software was used for meta analyses.Results Four-teen trials involving 1179 patients were include.The results of meta analyses showed that auricular pressure therapy was similar to western medicine in anti hypertensive effect;there were significant differences between auricular pressure therapy plus western medicine versus western medicine in anti hypertensive effect.Total effect rate of auricular pressure therapy plus western medicine were higher than western medicine in improving symptoms.No adverse events were reported in included RCTS.Conclusion Auricu-lar pressure therapy is safe and effective for mild to moderate essential hypertension.However,due to low quality of included stud-ies,rigorously designed RCTs are needed to confirm the conclusions.