动脉粥样硬化病人动脉硬化程度与血压、血清蛋白的相关性研究

摘要

Objective To study the relationship among arterial elasticity and blood pressure,serum protein.Methods Three hundreds and four patients in the medical center of the Southern District of Guang’anmen Hospital of China Academy of Chinese Medical Sci-ences in July 2014 were enrol ed.Asking medical history,measuring height,weight,body mass index (BMI),blood pressure,blood routine and biochemical indicators,and applying Omron BP 203RPEⅢ arteriosclerosis Arterial elasticity detector to test their arterial elasticity of the crowd,according to brachial ankle pulse wave velocity(baPWV)artery into normal group(n=117),mild sclerosis group (n=112)and hardening group (n=75),clinical indicators were compared between the three groups.Results Compared to normal group,systolic blood pressure (SBP)in mild sclerosis group and sclerosis group were significantly different,respectively,the difference was statistical y significant (P<0.01).Compared to normal group,diastolic blood pressure (DBP)mild sclerosis group and sclerosis group were significantly different,respectively,the difference was statistical y significant (P<0.01).Compared to normal group,serum albumin(ALB)in mild sclerosis group and sclerosis group were significantly different,respectively,the difference was statistical y significant(P<0.05);compared to normal group,serum globulin (GLB)in mild arterial sclerosis and normal group group were significantly different,and the difference was statistical y significant (P<0.05).Conclusion analysis showed that three groups of age,SBP,DBP,GLB and baPWV was positively correlated while ALB and baPWV were negatively correlated.TP was no correlation with baPWV.Conclusion Serum levels of ALB,GLB could be used to estimate the early arterial elasticity,and we should strengthen the detection of arterial elasticity elderly,prevent the occurrence of atherosclerosis.%目的：研究某体检人群动脉弹性与血压、血清蛋白的关系。方法选择2014年7月在中国中医科学院广安门医院南区的体检者304例，询问病史、测量身高、体重、体重指数(BMI)、血压等，检测血常规、生化等指标，应用欧姆龙 BP 203RPEⅢ动脉硬化检测仪检测体检人群的动脉弹性，根据肱踝脉搏波传导速度(baPWV)分为动脉正常组(117例)，轻度硬化组(112例)与硬化组(75例)，将3组临床指标比较研究。结果3组收缩压(SBP)比较，轻度动脉硬化组、高度动脉硬化组均与动脉正常组比较，差异有统计学意义(P<0.01)；3组舒张压(DBP)相比，轻度硬化组与硬化组与高度动脉动脉正常组比较，差异有统计学意义(P<0.01)；3组血清白蛋白(ALB)相比，动脉正常组与轻度动脉硬化组、轻度动脉硬化组与高度动脉硬化组比较差异有统计学意义(P<0.05)；3组血清球蛋白(GLB)相比，动脉正常组与轻度动脉硬化组比较差异有统计学意义(P<0.05)。相关性分析：3组年龄、SBP、DBP、GLB与 baPWV呈正相关；ALB与 baPWV呈负相关；而 TP则与 baPWV无相关性。结论血清 ALB、GLB可用于早期估测动脉的弹性。应加强对老年人动脉弹性的检测，预防动脉硬化的发生。