川崎病又称小儿皮肤黏膜淋巴结综合征,是儿科常见的急性血管炎综合征,病变主要累积中、小动脉,尤其是冠状动脉(冠脉),是小儿冠脉病变的主要原因,也是成年后发生冠心病的潜在危险因素.回顾性分析1例川崎病并发冠脉瘤患儿4年后发生心脑血管损害的临床资料及治疗,并分析相关文献,探讨川崎病并发冠脉瘤患儿发生心脑血管损害的临床特点.提示对于川崎病患儿应早期采取正规治疗以及定期随访,长期监测冠脉变化情况,以减少心脑血管意外事件的发生.%Kawasaki disease, also known as infantile skin mucous membrane lymph node syndrome, is an acute vasculitis syndrome in pediatricdepartment. The lesion mainly involves medium and small arteries, particularly the coronary artery, being a major cause of pediatric coronary lesion and also a potential risk factor of coronary heart disease during later adulthood. Here the clinical data and treatment of one case of Kawasaki disease complicated with coronary aneurysm and 4 years later the occurrence of cardiocerebrovascular lesion (CCVL) were retrospectively analyzed, and the related literatures were reviewed and analyzed to approach the clinical characteristics of this disease complications. It is suggested that at early stage regular treatment should be applied and afterwards periodical follow-up should be performed; long-term monitoring coronary changes ought to be carried out to decrease the occurrence of CCVL accident.
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