季鏻阳离子柱撑磷酸锆的热稳定性及抗菌活性

摘要

采用离子交换法将不同含量的十二烷基三丁基溴化鏻(DDTB)插入层状磷酸锆得到一种耐高温且具有优良抗菌性能季鏻阳离子柱撑磷酸锆(DDTB-ZrPs).通过热重分析(TGA)、红外分析(FTIR)、X射线衍射法(XRD)和透射电镜(TEM)对DDTB-Zrps的结构进行了表征,并测定了DDTB-ZrPs的最低抑菌浓度.结果表明,季鏻盐已经成功插入层状α-鏻酸锆的层间,DDTB-ZrPs的层间距随着季鏻盐含量的增加而增加.DDTB-ZrP-1(DDTB含量为5.61wt%)的热稳定性最好,有机物失重5%时温度可达320℃,最大热分解率温度达384℃.DDTB-ZrP-6(DDTB含量为26.46wt%)显示出良好的长效抗菌活性,对大肠杆菌和金黄色葡萄球菌的最低抑菌浓度分别为80和15 mg·L-1.进一步的研究表明,随着DDTB含量的增加,DDTB-ZrPs的热稳定性降低而抗菌活性增强.%Dodecyl tributyl phosphonium bromide pillared layered α-zirconium phosphate (DDTB-ZrPs) wasprepared by introducing dodecyl tributyl phosphonium bromide (DDTB) into layered α-zirconium phosphate (ZrP)through ion-exchange method, and the resulting DDTB-ZrPs were characterized by FTIR, XRD, TEM, and TGA/DTG techniques. Minimum inhibitory concentration (MIC) was used to evaluate antibacterial activity. The results show that the DDTB are intercalated into ZrP and the basal spacing of DDTB-ZrP is enlarged with the increase in phosphonium salt content. DDTB-ZrP-1 with 5.61wt% of DDTB, shows the highest temperature resistant, the 5%weight loss temperature could be up to 320 ℃ and the max decomposition rate temperature reaches to 384℃.DDTB-ZrP-6 with 26.46wt% of DDTB displays the highest antibacterial activity for the MIC against E. coli and S.aureus of 80 and 15 mg·L-1, respectively. Further analyses indicate that along with the increase in the content of DDTB, the thermostability of DDTB-ZrPs decreases and the antibacterial activity improves.