11例不明原因非典型肺炎患者临床特点分析

摘要

目的：了解不明原因非典型肺炎患者的临床表现和流行病学特点，提高对该病的认识。方法对11例集中暴发的不明原因非典型肺炎患者的临床资料及治疗效果进行回顾性分析。结果11例患者中，男性3例，女性8例，年龄22～32岁，平均年龄26．3岁，患者均同时来源于同一单位，主要临床表现为发热、咳嗽、咳痰、胸闷，无呼吸困难；CT 扫描均显示两肺纹理增粗，一叶或多叶可见斑片状及结节状影，边缘模糊，部分患者纵膈内可见小结节影，胸腔内未见游离液体密度影；外周血白细胞计数正常或降低，常见非典型肺炎病原体检测均阴性。所有患者住院隔离治疗，给予抗感染治疗均痊愈出院。结论此组患者病因未明，发病人群呈聚集性，肺部均表现为片状影，临床症状轻，应用抗感染治疗预后好，符合非典型肺炎的特点。%Objective To investigate clinical manifestations and epidemiological characteristics of patients with atypical pneumonia of unknown cause.Methods Clinical data and therapeutic effect of 11 cases of concentrated out-break of atypical pneumonia with unknown cause were retrospectively analyzed.Results 11 patients(3 males and 8 females,age 22-32 years,average age 26.3 years)were admitted in the hospital,they worked at the same institution and occurred atypical pneumonia during the same period,the main clinical manifestations were fever,cough,expec-toration,chest distress,but without difficulty in breathing.Computed tomography (CT)findings were as follows:increased bilateral lung markings,patchy and nodular shadows at single or multiple lobes,with blurred edge,small nodule shadow at mediastinum,no free liquid density shadow in the thoracic cavity;white blood cell count in periph-eral blood was normal or decreased,detection results of common atypical pneumonia pathogens were negative.All hospitalized patients were isolated and given treatment,and were cured and discharged after receiving anti-infection treatment.Conclusion This group of patients are with unknown etiology,atypical pneumonia occurs in an aggrega-ted population,lung is characterized by patchy shadow,clinical symptoms are mild,prognosis is good after anti-in-fection treatment,and is in accordance with the characteristics of atypical pneumonia.