睾丸穿刺取精术对非梗阻性无精子症患者性功能影响的临床研究

摘要

To study the effect of testicular sperm aspiration puncture on the sexual function of patients with non-obstructive azoospermia.Methods:125 patients with non-obstructive azoospermia,with an average age of 28.2 years,were selected and checked to have no sperm in semen with a centrifugation of semen.All the 125 pa-tients underwent testicular biopsy surgery:58 cases were of testicular sperm,and 67 cases of testicular azoospermia. The patients were divided into two groups of sperm group and no sperm group.The levels of hormone serum follicle stimulating hormone (FSH),luteinizing hormone (LH)and total testosterone (TT))Horizontal as well as the e-rectile function (IIEF-5 )and HADS of patients in both groups before and after surgery was compared.Results:For both groups,(1 )difference in the levels of hormone serum follicle stimulating hormone (FSH),luteinizing hor-mone (LH)and total testosterone (TT))before and after treatment was significant (P<0.05);(2)difference in the index of erectile function before and after treatment was significant (P<0.05);(3)difference in the anxiety, depression scores before and after treatment was significant (P<0.05 ).Conclusion:Testicular sperm retrieval puncture technique exerts significant impact on the hormone levels,erectile function and psychological status of pa-tients with non-obstructive azoospermia.%目的：研究睾丸穿刺取精术对非梗阻性无精子症患者性功能的影响。方法：本研究选择的对象为125例非梗阻性无精子症患者，平均年龄28．2岁，均经过精液的离心检查之后，确定精液中无精子。125例非梗阻性无精子症患者均行睾丸穿刺手术，手术中报告：睾丸内有精子58例、睾丸内无精子67例。将125例非梗阻性无精子症患者均行睾丸穿刺手术，分别测定手术前、手术后两组患者体内的性激素血清卵泡刺激素（FSH）、黄体生成素（LH）、总睾酮（TT））水平、手术前后患者的勃起功能（IIEF-5）、手术前后患者的焦虑抑郁情况（HADS）。结果：（1）患者体内的性激素血清卵泡刺激素（FSH）、黄体生成素（LH）、总睾酮（TT））水平在治疗前后相比有显著性差异（P＜0.05）；（2）患者的勃起功能指数在治疗前后相比有显著性差异（P＜0．05）；（3）两组患者焦虑、抑郁评分在治疗前后相比有显著性差异（P＜0．05）。结论：睾丸穿刺取精术对非梗阻性无精子症患者体内的性激素水平、勃起功能以及患者的心理状况有显著性的影响。