心理护理干预辅助治疗急性胰腺炎患者的疗效及对血清炎性因子的影响

摘要

目的 探讨对急性胰腺炎患者应用生长抑素、奥美拉唑治疗后,配合心理护理干预对其临床疗效以及血清炎性因子的情况.方法 选取2016年5月～2017年5月本院收治的90例急性胰腺炎患者,采用随机数表法分为对照组(生长抑素、奥美拉唑与常规护理)和观察组(生长抑素、奥美拉唑与心理护理干预联合治疗),每组患者45例.对比治疗后患者的临床症状恢复情况,以及焦虑等负性情绪的影响情况.结果 经治疗后,观察组患者精神支持、心理疏导、用药安全性以及穿刺护理显著优于对照组患者,差异均具有统计学意义(P＜0.05);观察组患者的C反应蛋白(CRP)(40.28 ± 9.11)mg/L、IL-6(44.81 ± 5.99)ng/L、IL-10(46.55 ± 2.21)ng/L以及TNF-α(51.77 ± 6.24)ng/L明显优于对照组患者的CRP(60.31 ± 8.22)mg/L、IL-6(61.88 ± 6.01)ng/L、IL-10(52.75 ± 3.81)ng/L以及TNF-α(67.81 ± 9.994)ng/L;观察组患者腹胀腹痛缓解时间(2.88 ± 0.43)d、肠道功能恢复时间(1.44 ± 0.38)d以及住院时间(12.87 ± 2.55)d显著短于对照组患者的腹胀腹痛缓解时间(4.56 ± 0.23)d、肠道功能恢复时间(3.81 ± 0.54)d以及住院时间(18.99 ± 3.01)d,差异均具有统计学意义(P＜0.05).结论 对于急性胰腺炎患者,采用生长抑素、奥美拉唑与心理护理干预联合治疗,可有效消除血清内炎性因子,提高患者护理满意度,有较高临床应用价值.%Objective To explore the clinical efficacy and serum inflammatory factors of somatostatin and omeprazole after acute pancreatitis.Methods From May 2016 to May 2017,90 cases of acute pancreatitis in our hospital were enrollde and randomly divided into the control group(somatostatin,omeprazole combined with routine treatment)and the observation group(somatostatin,omeprazole combined with psychological nursing intervention treatment),45 cases of patients in each group.The recovery of clinical symptoms and the influence of negative emotions such as anxiety were compared after the treatment.Results After the treatment,the mental support,psychological counseling,medication safety and puncture nursing were significantly better in observation group than those in the control group,and the differences were statistically significant(P ＜ 0.05).The expressions of CRP(40.28 ± 9.11)mg/L,IL-6(44.81 ± 5.99)ng/L,IL-10(46.55 ± 2.21)ng/L and TNF-α(51.77 ± 6.24)ng/Lin observation group were significantly lower than those in control group with CRP(60.31 ± 8.22)mg/L,IL-6(61.88 ± 6.01)ng/L,IL-10(52.75 ± 3.81)ng/L and TNF-α(67.81 ± 9.994)ng/L.The abdominal pain relief time(2.88 ± 0.43)d,intestinal function recovery time(1.44 ± 0.38)d,hospitalization time(12.87 ± 2.55)d in observation group were significantly shorter than the abdominal pain relief time(4.56 ± 0.23)d,intestinal function recovery time(3.81 ± 0.54)d,hospitalization time(18.99 ± 3.01)d in control group,and the differences were all statistically significant(P＜0.05).Conclusion In patients with acute pancreatitis,the combination treatment of somatostatin,omeprazole and psychological nursing can effectively eliminate inflammatory factors in the serum,improve patient satisfaction and have high clinical application value.