臂踝脉搏波传导速度对心血管疾病风险评估的研究进展

摘要

颈动脉-股动脉脉搏传导速度已在西方国家广泛应用并且成为大动脉僵硬度测量的金标准,由于技术难度等原因,这项测量在我国并未广泛开展.臂-踝脉搏波传导速度具有简单经济、无创及可重复性强等优点,近年来已开展广泛研究.同时评价踝臂指数(ABI)可实现高风险人群的进一步风险分层,这项特征对暴露于多重风险并患有多血管疾病的高龄人群的健康管理必不可少.%It is urgent to establish a model of cardiovascular risk assessment.Pulse wave velocity(PWV),which is increased along with advancing age,high blood pressure,diabetes,and other traditional cardiovascular risks,could be used as a risk marker for global cardiovascular risk assessment.Carotid-femoral PWV has been widely applied in Western countries and used as a gold standard for arterial stiffness.However,carotid-femoral PWV has not been widely carried out in China,possibly because of methodological difficulties.Brachial-ankle PWV (baPWV)is simple,economical,non-invasive and easily repeatable,and many researches on baPWV have been widely studied in recent years.Many evidences have indicated that baPWV is positively and independently correlated with the most traditional cardiovascular risk factors and arteriosclerosis-detecting indexes.Moreover,the simultaneous evaluation of the ankle-brachial index(ABI)could allow further risk stratification of high-risk individuals,which is indispensable for the management of aged people with multiple risks and many vascular diseases.