Objective To analyze the prevalence and characteristics of skin diseases in elderly patients with type 2 diabetes mellitus (T2DM).Methods Clinical out patient records for both elderly and non-elderly individuals with T2DM were collected from the dermatology department of Beijing Hospital.Statistical comparisons were performed between the elderly group and the non-elderly group on the prevalence of common skin complications and disease characteristics.Analysis was performed in the elderly group to identify any association of common skin disorders with gender,age,duration of T2DM,or level of glycosylated hemoglobin (HbA1c).Results Among 679 elderly T2DM cases,pruritus was the most common complication (26.1％),followed by eczema (21.t ％) and tinea pedis/onychomycosis (18.3％).Pruritus was more prevalent in the elderly group (177 cases,26.1％) compared to the non-elderly group (34 cases,9.8％) (x2 =6.006,P＜0.01).On the other hand,tinea pedis/onychomycosis was less prevalent in the senior group (124 cases,18.3 ％) than in the non-senior group (112 cases,32.2 ％) (x2 =37.437,P＜0.01).In the senior group,pruritus was more prevalent among male patients (105 out of 358 cases,29.3％) than among female patients(72 out of 321 cases,22.4％) (x2 =4.181,P =0.041).On average,patients with eczema were older[(72.3 ± 2.2)years] and had a longer history of T2DM [(8.3 ± 0.3)years] compared with patients without eczema[age:(65.2±1.9)years,history of T2DM:(5.2±0.1)years] (t=1.250,P=0.023 for age;t=1.680,P=0.033 for disease duration).Patients with tinea pedis/onychomycosis had higher HbA1c levels (6.7 ± 0.4) ％ than patients without tinea pedis/onychomycosis (6.1 ± 0.3) ％ (t =0.790,P＜0.01).Conclusions Pruritus is the most common skin complication in elderly patients with type 2 diabetes and is more common in elderly patients and male patients.Risk factors for developing eczema in elderly patients with type 2 diabetes may include older age and long disease duration.High levels of glycosylated hemoglobin in elderly patients with type 2 diabetes indicates increased risk for foot fungi infections.%目的 分析老年2型糖尿病患者合并皮肤疾病的状况. 方法 收集我院皮肤科门诊的老年组和非老年组2型糖尿病患者的临床资料,分析老年和非老年2型糖尿病患者合并常见皮肤病患病率的差异及老年患者合并的常见皮肤病与性别、年龄、病程和糖化血红蛋白水平之间的关系.结果 在679例老年2型糖尿病患者中,瘙痒症的患病率(26.1％)最高,其次为湿疹(21.1％)和足甲癣(18.3％).老年组中瘙痒症患者177例,占26.1％,高于非老年瘙痒症患者34例(9.8％);老年组中足甲癣患者有124例,占18.3％,低于非老年组112例(32.2％)(x2=6.006、37.437,均P＜0.01).老年组男性瘙痒症的患病率29.3％(105/358),高于女性22.4％(72/321)(x2=4.181,P=0.041);湿疹患者的平均年龄(72.3±2.2)岁和平均病程(8.3±0.3)年,均大于无湿疹患者(65.2±1.9)岁和(5.2±0.1)年(t=1.250、1.680,P=0.023、0.033);足甲癣患者糖化血红蛋白水平(6.7±0.4)％,高于无足甲癣者(6.1±0.3)％(t=0.790,P＜0.01). 结论 瘙痒症是老年2型糖尿病患者最常见的皮肤并发症,患病率明显高于非老年组,且男性患病率高于女性;高龄和长病程可能为老年2型糖尿病患者并发湿疹的易感因素;糖化血红蛋白的水平越高,老年2型糖尿病患者合并足甲癣的风险越大.
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