Objective To assess the distribution of left atrial volume indication(LAVI) for echocar-diogrphy and the early mitral diastolic flow peak value(E) and mitral tissue Doppler early dias-tolic peak value(EM) ratio in normal people and their relation. Methods A total of 650 healthy individuals were randomly divided into 24 - 30 years old group (w = 34) , 31 - 40 years old group (w = 59),41 - 50 years old group(rc = 107) , 51 - 60 years old group(w= 172) , 61 - 70 years old group(ra=131) ,71 - 80 years old group(?7 = 128) ,and 81 - 90 years old group(n= 19) according to their age. Ratio of left ventricular diastolic function indication(E) and mitral diastolic flow peak . Value (A) ,and Em,E/Em, LAV, LA VI were measured by 2D echocardiography and tissue Doppler examination,respectively,with their change observed in different age groups. Results The LAV, LAVI,and E/Em tended to increase while the E/A and Em tended to decrease in an age-dependent manner(P<0. 001). The LAVI was positively related with the E/Em in all subjects(r = 0. 212,P<0. 01) and with the LAV and E/Em in 81 - 90 years old group(r = 0. 682,P<0. 01;r= 0. 560,P<0. 05). Conclusion The LAV,LAVI,and E/Em increase while the E/A and Em decrease in normal people in an age-dependent manner. Combined LAVI and E/Em contributes better to the assessment of left ventricular diastolic function in people with their age 2>81 years.%目的 评价超声心动图指标左心房容积(left atrial volume,LAV)指数(LAVI)与反映左心室充盈压的二尖瓣舒张早期血流峰值(E)和组织多普勒二尖瓣环舒张早期峰值速度(Em)比值在正常人群中的分布及关系.方法 随机调查正常人群650例.按年龄分为7组,24～30岁组34例,31～40岁组59例,41～50岁组107例,51～60岁组172例,61～70岁组131例,71～80岁组128例,81～90岁组19例.用二维超声及组织多普勒的方法检测左心室舒张功能指标E与左心室二尖瓣舒张晚期血流峰值(A)的比值、Em、E/Em、LAV、LAVI,观察上述指标在不同年龄组的变化.结果 各组随年龄增长,LAV、LAVI、E/Em呈增高趋势,而E/A、Em呈降低趋势,差异有统计学意义(P＜0.01).整体人群LAVI与E/Em呈正相关(r=0.212,P＜0.01).81～90岁组LAVI和LAV与E/Em呈正相关(r=0.682,P＜0.01；r=0.560,P＜0.05).结论 正常人群LAV、LAVI、E/Em随年龄增长呈增高趋势,E/A、Em随年龄增长呈降低趋势.年龄≥81岁人群应用LAVI与E/Em相结合评价左心室舒张功能意义更大.
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