结肠癌干细胞标记物研究进展

摘要

Prevention and treatment of tumor metastasis are important for the therapy of colon cancer. The discovery of stem cell markers provides a new approach for radical treatment of cancer. So far,the colon cancer stem cell markers discovered included several membrane protein molecules,transcription factors and related signal pathway. Exploration of colon cancer stem cell markers could contribute to the treatment of colon cancer and improve the survival rate and life quality of patients. This article reviewed the advances in study on colon cancer stem cell markers.%防治肿瘤转移是结肠癌治疗的重点和难点。干细胞标记物的发现为根治肿瘤提供了新途径，目前发现的结肠癌干细胞标记物包括多种膜蛋白分子、转录因子以及相关信号通路等。探寻结肠癌干细胞标记物有助于根治肿瘤，提高患者生存率和生存质量。本文就结肠癌干细胞标记物研究进展作一综述。