目的 探究不同文化程度的冠状动脉(冠脉)支架术后患者对双联抗血小板聚集治疗(DAPT)依从性的影响.方法 前瞻性入选经皮冠脉介入术(PCI)治疗的老年患者1423例,按文化程度分为:文盲、小学、初中、高中、大学及以上,共5组,PCI术后1年随访患者DAPT依从性情况.结果小学及以下文化患者完全依从占70.9%,初中文化患者占80.4%,高中学历患者占88.9%,大学及以上学历患者占95.8%(P＜0.05);支架内血栓14例,均发生在不依从患者中,发生率为1%,其中小学学历的患者中血栓发生率最高,大学学历的患者最低.结论 不同文化水平对冠脉支架术后患者DAPT依从性影响存在着显著差异,文化程度低的患者依从性较差,出现不良事件几率高,对其进行适宜的相关宣教,可提高依从性.%Objective To investigate the influence of different educational levels on the compliance of dual anti-platelet therapy (DAPT) in patients after PCI. Methods The elderly patients (n=1423) under gone PCI were prospectively chosen, and divided, according to their educational levels, into group 1 (illiteracy), group 2 (educated in primary school), group 3 (educated in middle school), group 4 (educated in high school) and group 5 (university diploma or above). All patients were followed up for surveying DAPT compliance for 1 y after PCI. Results The percentage of patients with complete DAPT compliance was 70.9% in groups 1 and 2, 80.4% in group 3, 88.9% in group 4 and 95.8% in group 5 (P<0.05). There were 14 cases of in-stent thrombosis all in non-compliance patients, and incidence was 1%. The incidence of thrombosis was the highest in group 2 and was the lowest in group 5. Conclusion The influence of different educational level on DAPT compliance has significant difference in patients undergone PCI. The patients with lower educational level have poor compliance and higher incidence of adverse events. Their compliance can be improved after appropriate education.
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