目的 探索影响尿碘水平的相关因素及造成尿碘异常的高危因素.方法 在上海交通大学医学院附属新华医院体检中心随机抽取12家单位994名正常成年人,平均年龄(41.8±10.5)岁.收集晨尿,并进行性别、年龄、甲状腺疾病史、24h饮食回顾等问卷调查,采用Empower(R) 软件进行logistic分析.结果 人群尿碘中位数为193.0 μg/L;调整混杂因素后发现性别(P=0.000)、家庭人均月收入(P=0.000)、使用含碘盐(P=0.041)、食用海带(P=0.000)与尿碘水平相关;每月碘盐摄入量多和进食海带致使碘过量(尿碘＞300 μg/L)发生的危险度明显增高:每月(每人)食用含碘盐量≥165 g,OR=24.3(95％CI:1.1～523.8,P＜0.05);前一天进食海带者,OR=9.6(95％CI:2.6 ～ 35.1,P＜0.001).结论 性别、家庭人均月收入、摄入含碘盐、食用海带是尿碘水平的独立影响因素;部分人群碘过量可能与进食碘盐及海带量多相关.%Objective The objective of this study was to analyze the related factors that influencing the level of urinary iodine (UI).Methods 994 adult cases were selected from medical centers.Morning urine was collected and questionnaire including age,sex,family medical history of thyroid disease administered.Information on previous 24-hour consumption of iodine-containing foods was collected.Data was analyzed by Empower(R) software with logistic model.Results The median UI level was 193.0 μg/L.After adjusting for potential confounders,gender (P=0.000),family monthly income per capita (P=0.000),the amount of iodized salt intake (P =0.041),and eating kelps (P=0.000) appeared to be associated with the level of UI.Risk regarding the prevalence of excess UI (＞ 300 μg/L) increased with the increasing amount of salt and kelp consumption:salt consumption ＞165 g/m (OR=24.3,95％CI:1.1-523.8,P＜0.05) ; kelp consumption (OR=9.6,95％CI:2.6-35.1,P＜0.001).Conclusion UI was associated with factors as:gender,family monthly income per capita,intake of iodized salt and the amount of kelp consumption.Excessive intake of iodine might be associated with high intake of iodized salt and kelp.
展开▼
