目的 了解中国不同地区女性性工作者(FSW)人群新型毒品使用情况及其对梅毒感染的影响.方法 5个调查城市(长春、兰州、武汉、杭州、广州)分别绘制FSW人群活动场所分布图,并将场所分层按比例抽取FSW,进行问卷调查和梅毒血清学检测.采用logistic回归模型分析梅毒感染和新型毒品使用的相关因素.结果 共招募1 630名FSW,其中120人(7.4％)过去12个月曾使用过新型毒品,梅毒感染率为5.4％(88/1 630).FSW使用新型毒品组梅毒感染率为6.7％(8/120),与未使用新型毒品组感染率(5.3％,80/1 509)的差异无统计学意义.多因素logistic逐步回归分析结果显示调查地点、户口所在地、婚姻状况、受教育程度、过去12个月有性病症状、过去12个月曾注射吸毒与使用新型毒品相关.结论 FSW中新型毒品使用率较高,需更多研究探讨使用新型毒品对艾滋病胜病传播的影响.%Objective To understand the prevalence rates of club drug use and how it associated with syphilis infection among female sex workers (FSWs) in different areas of China so as to provide reference for developing intervention programs.Methods In each of the study site,different kinds of venues where FSWs solicited clients were mapped and grouped into three strata.The number of FSWs at each venue was enumerated.A stratified proportional sampling design was adopted to recruit FSWs.Questionnaire survey was conducted to gather data on demographic information,club drug use and sexual behaviors.Blood samples were taken and tested for syphilis.Factors associated with syphilis infection and club drug use were assessed using univariate and multivariate logistic regression models.Results Results of the 1 630 participants,120 (7.4％) used club drugs in the past 12 months,and 5.4％ (88/1 630) tested positive for syphilis.Syphilis positive rate was not significantly different between FSWs who used club drugs and those who did not.Data from multivariate logistic regression analysis indicated that club drug use was associated with following factors as sites of the study,hometown of the FSWs,marital status,education level,having had STD symptoms or history of injecting drugs in the past 12 months of the sex workers.Conclusion Club drug use was highly prevalent among FSWs.Further studies are warranted to fully explore the association between club drug use and the risk of HIV/STD transmission.
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