新疆哈萨克族成年人群最适腰臀围比切点值对预测高血压、糖尿病和血脂异常作用的研究

摘要

目的 探讨新疆哈萨克族成年人群最适WHR切点值对筛选心血管疾病高危人群的作用.方法 2007年10月至2010年3月开展新疆地区心血管风险调查(CRS),共选择具有代表性样本14 618人,其中哈萨克族4 094人,从中选取资料完整的4 004人作为研究对象,年龄35 ～ 88岁,平均48.60岁.测量并记录每名入组对象的血压、TC、TG、LDL-C、HDL-C和FPG.计算并记录不同WHR值所对应的心血管疾病危险因素的患病率、敏感度、特异度及在受试者工作特征(ROC)曲线上的距离.结果 (1)无论男性和女性,WHR值较高人群其高血压和高TG血症的患病率较高;(2)WHR值较高的女性,其高TC血症的患病率较高;(3)无论男性和女性,其高血压、血脂异常、糖尿病或≥2个危险因素在ROC曲线上的最短距离定为最适WHR切点值,男性为0.92和0.91,女性为0.86和0.85.结论 在≥35岁哈萨克族成年人群中需要采用较高的WHR切点值筛查心血管疾病风险人群.%Objective The aim of this study was to identify the appropriate cutoffs for waist-hip-ratio (WHR) for Kazakh adults at high risk of cardiovascular diseases in Xinjiang.Methods A Cardiovascular Risk Survey (CRS) study was carried out from October 2007 to March 2010,with 14 618 representative participants selected,including 4 094 Kazakhs.Complete data on 4 004 participants were gathered.The age span of the participants was from 35 to 88 years old with the mean age as 48.60 years.Anthropometric data,blood pressure,serum concentration of serum total cholesterol,triglyceride,low density lipoprotein cholesterol (LDL-C),high density lipoprotein cholesterol (HDL-C) and fasting glucose were documented.Prevalence rate,sensitivity,specificity and distance on the receiver operating characteristic (ROC) curve of each WHR values were calculated.Results 1) The prevalence rates of hypertension,hypertriglyeeridemia were high,also with higher WHR seen in both men and women.2) The prevalence of hypercholesterolemia was high with higher WHR seen in women.3) The shortest distances in the receiver operating characteristic curves for hypertension,dyslipidemia,diabetes,or ≥2 of these risk factors suggested that the WHR cutoffs were 0.92 or 0.91 for men and 0.86 or 0.85 for women.Conclusion Higher cutoff for WHR was needed in the identification of patients over 35 at high risk of cardiovascular disease among Kazakh population.