哈尔滨市男男性行为人群HIV新发感染及失访影响因素分析

摘要

Objective To estimate the incidence of human immunodeficiency virus (HIV) infection among men who have sex with men (MSM) and its related factors in Harbin,Heilongjiang province.Methods A total of 661 MSM were recruited at baseline study from April to June 2013,and followed at 6 months,12 months,and 18 months periods,respectively.Face to face questionnaire interviews were conducted and venous blood was collected for HIV testing among these people.Univariate logistic regression model was used to identify the factors associated with lost-to-follow-up in the cohort.Results At the end of 18-month follow-up period,the HIV incidence density in the cohort was 4.23/100 person year (95％ CI:2.91/100 person year-5.93/100 person year),with the follow-up rate of loss as 15.4％.Factors as failed to receiving the intervention programs,being at older age,with higher education level and receiving no HIV testing in this MSM community,were related to the loss of follow-up.Conclusion The HIV incidence rate was high among the MSM in Harbin.MSM community based cohort study could improve the efficiency on the study for the problems of follow-up.%目的 了解黑龙江省哈尔滨市MSM人群中HIV新发感染率及失访影响因素.方法 2013年4-6月在哈尔滨市MSM人群中招募661人进行前瞻性调查,分别于6、12、18个月进行随访,入组及随访时均对调查对象进行面对面问卷调查,并采集静脉血进行HIV抗体检测,计算发病密度.利用logistic回归模型探讨MSM人群队列研究中失访的影响因素.结果 随访至18个月,调查对象HIV发病密度为4.23/100人年(95％CI:2.91/100人年～5.93/100人年),队列失访率为15.4％.未接受过干预、高年龄组、低学历者及非男男同志社区组织的研究对象易失访.结论 MSM人群HIV新发感染率较高,积极依托社区组织能提高该人群随访率.