Objective: To investigate the usage of antibiotics in treatment of infantile acute diarrhea in our hospital and provide reference for clinical rational administration. Methods: The application of antibiotics in the treatment of 180 infantile inpatients with acute diarrhea from October 2010 to March 2011 was investigated retrospectively, and the basic situation of the patient diagnosis, pathogeny examination,outcomes and the use of the antibiotics in infantile patients with acute diarrhea were statistically analysed. Results: Among 180 patients, 135 patients received antibiotics (75.0%). Aztreonam took the highest proportion (49.39%) in use frequency of antibiotics. In terms of drug combination (14.81%), the first place was piperacillin sodium and sulbactam sodium in combination with cefazolin sodium pentahydrate (4.44%). Conclusion: Clinical management of rational use of antibiotics must be enhanced because the application of antibiotics had unreasonable administration problems in terms of indications, drug selection, dosage, length of the treatment and combination therapy.%目的:了解我院小儿急性腹泻病住院患者应用抗菌药物的情况,为临床合理用药提供参考.方法:回顾性调查我院2010年10月-2011年3月180例小儿腹泻病住院患者抗菌药物的应用情况,从患者基本情况、诊断及病原学检查、患儿转归情况、抗菌药物应用基本情况等方面进行统计.结果:180例患儿中,有135例(75.0%)应用抗菌药物,应用频率最高的药物是氨曲南,占49.39%;联合用药率为14.81,以哌拉西林钠舒巴坦钠联用五水头孢唑啉钠最多,占4.44%.结论:我院治疗小儿腹泻病抗菌药物的应用在用药指征、品种选择、剂量、疗程及联合使用等方面存在不合理现象,需加强管理.
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