目的:比较三维适形放疗(3D2CRT)、多野照射和调强适形放疗(IMRT)对周围组织的损伤,并对其短期、长期疗效进行探讨.方法:120例胃癌术后患者随机分为多野照射组(A组)、3D2CRT组(B组)和IMRT组(C组),放疗结束后比较3组患者钡餐造影改善情况、症状缓解情况、肝功能、血常规、胰淀粉酶等指标,以及3年内的生存率和复发率,晚期迟发性放射性脊髓病的发病率.结果:3种放疗方法对胃癌术后的疗效均可排序为C组＞B组＞A组,对周围组织脏器的影响程度C组＜B组＜A组,且除钡餐结果外,其余指标B组、C组与A组相比均有显著差异(P＜0.05).结论:3D2CRT和IMRT较普通多野照射能更好提高胃癌疗效,且IMRT优于3D2CRT.%Objective; To compare multifield radiation therapy, three dimensional conformal radiation therapy (3D2CRT) and intensity-modulated radiotherapy(IMRT) on their curative effects and the damage effects to surrounding tissues, methods: 120 patients with gastric cancer were randomly treated with multifield radiation therapy, 3D2CRT and IMRT after operation. Compare symptomatic relief, barium meal results, blood routine, hepatic function, amylopsin, survival rate and relapse rate during three years, as well as incidence rate of tardive radiative myelopathy. Rexults: Curative effects of three therapy methods can be ranked as C>B>A, whereas the damage influences to surrounding tissues can be ranked as C展开▼
