干预冠心病危险因素对冠状动脉病变的影响

摘要

Objective To explore the influence of coronary angiography reexamination results of intervention for risk factors of coronary heart disease.Methods Seventy -four cases of coronary artery angiography reexamination were selected and divided into coronary artery lesion progression group (n =46)and no progression group (n =28)ac-cording to the results of coronary artery angiography,the difference of clinical data and smoking,hypertension,hyperlipi-demia,diabetes mellitus several risk factors of standard between two groups were compared.Results The hypertension (OR =13.51,95%CI:1.96 ~93.18),hyperlipidemia(OR =7.14,95%CI:1.39 ~36.75)and long interval time of coro-nary artery angiography (OR =1.07,95%CI:1.02 ~1.11)were risk factor of progression of coronary artery lesions.It can reduce the risk of disease progression by reduce risk factors (OR =0.04,95%CI:0.007 ~0.287).Conclusion The risk factors intervention for coronary heart disease can delay progression of coronary artery disease.%目的：探讨干预冠心病危险因素对冠状动脉病变的影响。方法根据74例冠脉造影复查结果分为冠状动脉病变进展组（n ＝46）与无病变进展组（n ＝28），分析两组患者的临床资料及吸烟、高血压、高脂血症、糖尿病几项危险因素达标等情况。结果高血压（OR ＝13．51，95％CI：1．96～93．18）、高脂血症（OR ＝7．14，95％CI：1．39～36．75）和复查冠状动脉造影间隔时间长（OR ＝1．07，95％CI：1．02～1．11）是冠状动脉病变进展的危险因素，而复查间期危险因素减少（OR ＝0．04，95％CI：0．007～0．287）则可以降低病变进展的风险。结论干预冠心病危险因素达标有利于延缓冠状动脉病变的进展。