首页> 外文期刊>中国化学工程学报(英文版) >重组大肠杆菌分批-补料高密度发酵生产类人胶原蛋白的动力学
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重组大肠杆菌分批-补料高密度发酵生产类人胶原蛋白的动力学

机译:重组大肠杆菌分批-补料高密度发酵生产类人胶原蛋白的动力学

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机译:The kinetics of batch and fed-batch cultures of recombinant Escherichia coli producing human-like collagen was investigated. In the batch culture, a kinetic model of a simple growth-association system was concluded without consideration of cell endogeneous metabolism. The cell lag time, the maximum specific growth rate and growth rates were set at (0.15, 0.2, 0.25h-1) by the method of pseudo-exponential feeding, and the expressions for the specific rate of substrate consumption, the growth kinetics and the product formation kinetics of each phase spectively. The model predictions are in good agreement with the experimental data.

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