Objective To investigate the clinical efficacy and nursing strategy of alprostadil and edaravone in the treatment of acute cerebral infarction (ACI). Methods 60 patients with ACI were randomly divided into observation group and control group with 30 cases in each group,the two groups were treated with Alprostadil Combined with edaravone, while the control group received routine care. The observation group received early rehabilitation nursing intervention on the basis of the control group nursing, the clinical efficacy, neurological deficit (NIHSS) score, Barthel index (BI) and complication rate were compared between the two groups before and after the nursing. Results The total effective rate and complication rate of the observation group were 93.33 and 10.00％ respectively, compared with 76.67％ and 23.33％ in the control group (P< 0.05);after nursing, the NIHSS score and BI index of the observation group were significantly better than that of the control group (P<0.05). Conclusion For ACI patients, given alprostadil combined with edaravone treatment and given early nursing intervention can significantly improve the clinical efficacy, improve the degree of neurologic impairment, improve the ability of daily life of patients and reduce the incidence of complications, worthy of promotion.%目的 探讨前列地尔联合依达拉奉治疗急性脑梗死(ACI)的临床疗效及护理对策.方法 将60例ACI患者随机分为观察组与对照组各30例,2组均给予前列地尔联合依达拉奉治疗,对照组给予常规护理,观察组在对照组护理基础上给予早期康复护理干预,对比2组临床疗效,护理前后神经功能缺损(NIHSS)评分、Barthel指数(BI)及并发症发生率.结果 观察组的总有效率和并发症发生率分别为93.33％、10.00％,与对照组的76.67％、23.33％比较差异具有统计学意义(P<0.05);观察组护理后的NIHSS评分低于对照组、BI指数高于对照组,2组差异均具有统计学意义(P<0.05).结论 对于ACI患者,在给予前列地儿联合依达拉奉治疗的同时,给予早期康复护理干预措施可显著提高临床疗效,改善患者神经功能缺损程度,提高患者日常生活能力和降低并发症的发生率,值得临床推广.
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