喘可治注射液雾化吸入对预防全麻术后呼吸道感染的临床效果观察

摘要

Objective To investigate the effect of chuan kezhi injection atomizing inhalation in the prevention of respiratory infection after general anesthesia postoperative.MethodsA total of 74 cases with fractures and brain surgery postoperative with intubation anesthesia from Jiaxing First Hospital were collected and randomly divided into two groups with 37 cases in each group.Patients in the control group were treated by routine atomizing inhalation, patients in the experiment group were treated by chuan kezhi injection atomizing inhalation, before and after treatment empty stomach sampled venous blood 5 mL, determined T cell subgroup, observed cough and expectoration eased and throat discomfort alleviated situations of the patients after operation 1 to 4 days, and compared the clinical efficacy.ResultsAfter treatment the effective rate of the experiment group 94.59% was higher than the control group 81.08%, with no statistical significance;the cough and expectoration symptoms eased of the experiment group were significant better than the control group after treatment 1, 2, 3d (P<0.05), the throat discomfort symptoms eased of the experiment group was significant better than the control group at treatment 3 d (P<0.05), after treatment the CD3+, CD4+/CD8+ and NK cell levels of the experiment group were higher than the control group(P<0.05).ConclusionChuan kezhi injection atomizing inhalation can effectively ease throat symptoms after general anesthesia, improve immune status, the effect is remarkable.%目的 探讨喘可治注射液雾化吸入对预防全麻术后呼吸道感染的临床效果观察.方法 选择嘉兴市第一医院择期插管全麻下行骨折及脑外科手术术后患者74例,按随机数字表法分为2组,对照组37例给予常规雾化吸入,研究组37例给予喘可治注射液雾化吸入,治疗前后均空腹抽取肘静脉血5mL,测定T细胞亚群状况,观察患者术后第1天至第4天咳嗽咳痰缓解和咽喉不适缓解情况,同时对比临床疗效.结果 研究组治疗后有效率94.59%,高于对照组治疗后有效率81.08%,但差异无统计学意义;研究组治疗1d、2d、3d时咳嗽、咳痰症状缓解显著优于对照组(P<0.05),研究组治疗3d时咽喉不适症状缓解显著优于对照组(P<0.05),研究组治疗后CD3+及CD4+/CD8+、NK细胞水平高于对照组(P<0.05).结论 采用喘可治注射液雾化吸入能有效缓解全麻术后咽喉症状,提高免疫力,效果显著.