异种脱细胞真皮基质预防腮腺术后味觉出汗综合征

摘要

目的：探讨应用异种脱细胞真皮基质预防腮腺肿瘤术后味觉出汗综合征的临床效果，以指导临床。方法：回顾性分析漯河市中心医院32例腮腺浅叶良性肿瘤病例，按照患者选用的治疗方法分为对照组20例和实验组12例，采用主观症状评价和 Minor 试验评估2组患者术后味觉出汗综合征的发生情况。结果：32例腮腺浅叶良性肿瘤病例术后均进行12～18个月的随访。实验组1/12例(8.5％)、对照组13/20例(65.0％)出现味觉出汗综合征主观症状，差异有统计学意义（P＜0.05)。Minor 试验中，试验组0/12例(0％)、对照组16/20例(80.0％)出现 Frey综合征客观症状，差异有统计学意义（P＜0.05)。结论：异种脱细胞真皮基质植入可以有效地预防腮腺肿瘤术后味觉出汗综合征的发生，值得临床推广和应用。%Objective To elvaluate the efficiency of heterogeneous acellular dermal matrix in the prevention of the Frey's syndrome after parotidectomy and put it in the clinic.MethodsBy means of retrospective analysis,32 patients with benign parotid tumors were divided into two groups according to their accepted treatment: the control group (n=20) and the observation group (n=12). The questionnaire and minor starch-iodion test were done to elvaluate the incidence of the Frey's syndrome.ResultsAll patients were followed up lasting 12 to 18 months. One of 12 (8.5%)in experiment group,13 of 20 (65.0%) in control group had subjective symptoms of Frey ’s syndrome. There was signiifcant difference between the two groups(P<0.05). By Minor’s starch iodine test,0 (0%) cases in experimental group and 16 (80.0%) cases in contro1 group had objective symptoms. The difference between the two groups was signiifcantly statistical (P<0.05).Conclusion Transplantation of heterogeneous acellular dermal matrix can efifciently prevent Frey's syndrome after parotidectomy.