Objective To explore the clinical effect of needle-inducing Jixuegan cream in patients with early hypertrophic scar. Methods 100 patients with early hypertrophic scars were treated in our hospital from June 2015 to June 2016 were randomly divided into two groups: observation group(n=50) and control group (n=50). The patients in observation group were treated with skin needle into Jixuegan cream ointment, the control group with Jixuegan cream ointment for treatment. The two groups of patients were treated for 2 courses of continuous. The vancouver scar scale (VSS), including the scar color, thickness, vascular distribution and softness, were compared between the two groups before and after treatment. The total effective rate and adverse reaction rate were compared between the two groups. Results There was no significant difference between the two groups before treatment (P>0.05). The VSS score of the observation group was significantly lower than that of the control group, the difference was statistically significant (P<0.05). The total effective rate of the observation group(80%) was higher than that of the control group(50%), the difference was statistically significant (P<0.05). The two groups of patients did not have serious adverse reactions. There was no significant difference in the incidence of adverse reactions between the two groups(P>0.05). Conclusion Skin needle into Jixuegan cream in the treatment of early hyperplastic scar is effective and safe, and worthy of popularization and application.%目的:探讨滚针导入积雪苷霜软膏在早期增生性瘢痕患者中的临床效果.方法:选取2015年6月至2016年6月接受治疗的早期增生性瘢痕患者100例作为研究对象,随机分为2组,观察组和对照组,每组50例.观察组患者采用皮肤滚针导入积雪苷霜软膏的方法进行治疗,对照组采用积雪苷霜软膏外涂治疗,对两组患者均进行2个疗程的持续治疗,比较两组患者治疗前后的温哥华瘢痕量表评分(Vancouver scar scale,VSS)(包括瘢痕色泽、厚度、血管分布和柔软度),治疗总有效率及不良反应发生率.结果:治疗前两组患者的温哥华瘢痕量表评分差异无统计学意义(P>0.05),治疗后观察组患者的VSS评分显著低于对照组,差异有统计学意义(P<0.05);观察组患者的治疗总有效率(80.00%)显著高于对照组(50.00%),差异有统计学意义(P<0.05);两组患者均未发生严重不良反应,其不良反应发生率差异无统计学意义(P>0.05).结论:皮肤滚针导入积雪苷霜软膏应用于早期增生性瘢痕患者,疗效显著,安全性好,值得推广应用.
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