血尿素氮/肌酐变化曲线在急性上消化道出血患者出血量估算中的应用

摘要

Objective To evaluate the application of blood urea nitrogen ( BUN ) /creatinine ( Cr ) curve in estimating the amount of bleeding in patients with acute upper gastrointestinal hemorrhage. Methods A total of 215 patients with acute upper gastrointestinal bleeding treated by the gastroenterology department of our hospital were divided into two groups according to the amount of bleeding: ＞ 800 ml ( 139 cases ) and ≤800 ml ( 76 cases ). Levels of BUN and Cr were determined at admission and 24, 48, 72, 96 hours after admission with the blood BUN/Cr ratio calculated and the curve made. Results BUN/Cr ratios at admission and 24, 48, 72, 96 hours after admission were ( 92. 6 ± 16. 0 ), ( 162. 3 ± 17. 9 ), ( 160. 2 ± 15. 6 ), ( 108. 2 ± 14. 2 ), ( 89. 6 ± 10. 6 ) and ( 71. 1 ± 16. 1 ), ( 122. 5 ±26. 7 ), ( 123. 5 ±25. 3 ), ( 84. 9 ± 16. 2 ), ( 74. 5 ± 14. 9 ) in the ＞ 800 ml group and the ^ 800 ml group respectively, with statistically significant differences between the two groups ( P ＜ 0. 05 ). Conclusion The peak of BUN/Cr ratio exceeds ( 160. 2 ± 15. 6 ) in patients with bleeding ＞ 800 ml and exceeds ( 123. 5 ±25. 3 ) in patients with bleeding ≤800 ml. Blood BUN/Cr curve is of great value in estimating the bleeding amount in patients with acute upper gastrointestinal bleeding.%目的 评价血尿素氮(BUN)/肌酐(Cr)变化曲线在急性上消化道出血患者出血量估算中的应用.方法 对本院消化内科收治的215例急性上消化道出血患者按照出血量分成两组:出血量>800 ml组(139例)和出血量≤800 ml组(76例).分别于入院时及入院后24、48、72、96 h测定血BUN、Cr水平,计算BUN/Cr比值,制成曲线.结果 出血量>800ml组患者入院时及入院后24、48、72、96 h的BUN/Cr比值分别为(92.6±16.0)、(162.3±17.9)、(160.2±15.6)、(108.2±14.2)和(89.6±10.6),出血量≤800 ml组分别为(71.1±16.1)、(122.5±26.7)、(123.5±25.3)、(84.9±16.2)和(74.5±14.9),两组比较差异均有统计学意义(P＜0.05＝.结论 出血量>800 ml的患者BUN/Cr峰值超过(160.2±15.6),出血量≤800 ml患者BUN/Cr峰值不超过(123.5±25.3),血BUN/Cr变化曲线在急性上消化道出血患者出血量估算中具有较高的实用价值.实用价值.