2型糖尿病共病抑郁症的危险因素分析

摘要

Objective To explore the clinical characteristic and relevant risk factors of comorbid type 2 diabetes and depression. Methods A total of 120 type 2 diabetes patients were evaluated via self - rating depression scale ( SDS ) and divided into the depression group and simple group, with the socio - demographic features of the two groups compared. Logistic regression analysis was applied to investigate the risk factors for complicated depression among diabetic patients. Results Of the 120 diabetic patients, 52 ( 43.3％ ) were with complicated depression and the other 68 were not. Single factor analysis revealed that the marital status, duration of diabetes, combined somatic disease, fasting blood glucose and glycated hemoglobin ( HbA1c ) were significantly different between the depression group and the simple group ( P ＜ 0.05 ) . Logistic regression analysis showed that marital status, somatic diseases and HbA1c were the main risk factors of complicated depression among diabetes patients ( P ＜0.05 ) . Conclusion Prevalence of depression is high among diabetic patients with; routine depression screening should be carried out in patients with insufficient family emotional support, somatic comorbidities, and high HbA1c levels.%目的 探讨2 型糖尿病共病抑郁症的临床特点及相关的危险因素.方法 选取120例2型糖尿病患者,均进行抑郁自评量表(SDS)评定,根据结果分为糖尿病伴抑郁症组和单纯糖尿病组,对两组患者的社会人口学资料和病情资料进行比较,采用Logistic回归分析探讨糖尿病并发抑郁症的危险因素.结果 120例糖尿病患者中,合并抑郁症者52例(43.3%),未合并抑郁症者68例.单因素分析发现婚姻状况、糖尿病病程、合并躯体疾病、空腹血糖和糖化血红蛋白(HbA1c)在糖尿病伴抑郁症组和单纯糖尿病组之间差异有统计学意义(P＜0.05).Logistic回归分析显示,婚姻状况、合并躯体疾病和HbA1c是糖尿病并发抑郁症的主要危险因素(P＜0.05).结论 糖尿病患者的抑郁症患病率较高;对家庭情感支持不足、躯体合并症多、高HbA1c水平的糖尿病患者应常规进行抑郁症筛查.