目的 对比分析聚桂醇注射液与无水乙醇治疗单纯性肾囊肿的临床疗效与安全性.方法 将单纯性肾囊肿患者分为聚桂醇组(28例)与无水乙醇组(22例).超声引导经皮肾穿,分别将聚桂醇注射液与无水乙醇溶液注入两组肾囊肿内,对比观察两组患者的不良反应及有效率.结果 聚桂醇组术后患侧腰部不适发生率35.7%(10/28),无水乙醇组术后患侧腰部不适发生率54.5%(12/22),两组间差异有统计学意义(P＜0.05).两组均未出现出血、感染等并发症.聚桂醇组6月随访有效率达96.4%(27/28),无水乙醇组有效率达95.5%(21/22),两组间差异无统计学意义(P＞0.05).结论 聚桂醇硬化剂治疗单纯肾囊肿的疗效与无水乙醇相同,但不良反应明显少于后者,是一种安全有效的硬化剂,有望在单纯肾囊肿的硬化治疗中成为无水乙醇的替代物.%Objective To investigate the clinical effects and safety of lauromacrogol injection and absolute alcohol injection for sclerotherapy of single renal cyst under guidance of intervenous ultrasound. Methods Fifty patients were divided into the treatment group ( 28 cases ) and the control group ( 22 cases ). The treatment group was treated with lauromacrogol injection and the control group was treated with absolute alcohol injection. The adverse effects and effective rates of the two agents in the two groups were observed and compared. Results The incidence of lumbar pain on the affiliated side was lower in the treatment group ( 10/28, 35. 7% ) than that in the control group ( 12/22, 54. 5% ) ( P <0. 05 ). After 6 monthsfollow - up, the effective rate was 96. 4% in the treatment group and 95. 5% in the control group, and there was no significant difference ( P > 0. 05 ). Conclusion Lauromacrogol injection has similar effect to absolute alcohol injection for sclerotherapy of renal cyst, but is safer.
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