颈动脉狭窄支架成形术实施前后患者定量脑电图分析研究

摘要

Objective To study the quantitative electroencephalogram(QEEG) power spectrum changes in patients with carotid stenosis before and after the carotid artery stenting(CAS) and explore its value for assessing the improvement in brain function in these patients after CAS.Methods This retrospective study was conducted in 36 patients performed CAS in Binzhou Medical University Hospital from January 2014 to October 2015.Electroencephalogram(EEG) was performed in the patients before and after the procedure and the results were recorded.The relative power ratio of (δ﹢θ)/(α﹢β)(DTABR) at bilateral prefrontal electrodes(FP1,FP2),central electrodes(C3,C4),occipital electrodes(O1,O2) and temporal electrodes(T3,T4) in the patients after CAS were calculated and compared with those before the procedure.Results Before the procedure,EEG results were normal in 9 cases,mild abnormalities in 15 cases,moderate abnormalities in 10 cases,and severe abnormalities in 2 cases;after the procedure,EEG results were normal in 12 cases,mild abnormalities in 17 cases,moderate abnormalities in 6 cases,and severe abnormalities in 1 case,which showed that the EEG results of the patients before and after the CAS had no significant differences(Z=-1.882,P=0.060).Compared with before the CAS,after the CAS,DTABR at bilateral occipital electrodes(O1,O2) did not change significantly(P>0.05),but the DTABR at bilateral prefrontal electrodes(FP1,FP2),central electrodes(C3,C4),and temporal electrodes(T3,T4) decreased substantially(P0.05);CAS实施后双侧前额区(FP1、FP2)、中央区(C3、C4)、颞区(T3、T4)DTABR均低于CAS实施前(P<0.05).结论 CAS实施前、后QEEG在前头部有明显变化,可能与颈动脉在头部血流分布特点有关.QEEG可作为评价重度颈动脉狭窄患者CAS实施前、后脑功能改善的有效参考指标之一.