经单侧鼻孔蝶窦入路显微切除垂体瘤38例分析

摘要

目的：分析经单侧鼻孔蝶窦入路显微切除垂体瘤的临床治疗效果。方法：选取2007-2010年毫州市人民医院神经外科收治的垂体瘤患者38例，经单侧鼻孔蝶窦入路显微切除垂体瘤手术治疗，治疗后观察切除结果和临场症状改善情况，并发症发生率和住院时间。结果：38例患者手术治疗顺利，全切除31例，次全切6例，部分切除1例；患者术后临床症状均获得不同程度改善；治疗术后发生暂时性尿崩症5例，出现一过性脑脊液鼻漏2例，出现垂体功能低下1例，经治疗后明显好转。术后住院时间小于7 d 34例，只有4例住院超过7 d，10 d内也均康复出院。结论：经侧单侧鼻孔蝶窦入路显微切除垂体瘤具有微创、治愈率高、住院时间短、准确性高及并发症少，是垂体瘤手术治疗的首选。%Objective:To analyze the clinical effect of unilateral nostril transsphenoidal microsurgery resection for pituitary tumors.Methods:From 2007 to 2010 the People’s Hospital of Bozhou Neurosurgery treated 38 patients with pituitary tumors by unilateral nostril transsphenoidal microsurgery resection of pituitary tumors through the line of treatment,the treatment results were observed after resection and spot improvement of symptoms incidence of complications and hospitalization time. Results:38 patients surgery went well,subtotal resection in 31 cases,subtotal resection in 6 cases,partial resection of one case;Patients with varying degrees of clinical symptoms were improved;Treatment of postoperative transient diabetes insipidus occurred in 5 patients,cerebrospinal fluid rhinorrhea appeared to have 2 cases,1 case of hypopituitarism after treatment significantly improved.Less than seven days after hospital discharge in 34 cases,only four cases hospitalized for more than 7 days,10 were also discharged within.Conclusion:The side of unilateral nostril transsphenoidal pituitary tumor resection with microscopic invasive,high cure rate,shorter hospital stay, high accuracy and fewer complications,pituitary tumor surgery is the treatment of choice.