首页> 中文期刊> 《中外医学研究》 >左炔诺孕酮宫内缓释系统治疗子宫腺肌症的临床疗效观察

左炔诺孕酮宫内缓释系统治疗子宫腺肌症的临床疗效观察

         

摘要

Objective:To study clinical effect of Levonorgestrel-releasing Intrauterine System in adenomyosis.Method:40 cases of uterine adenomyosis patients in our hospital from January 2012 to March 2013 were admitted for the study,the Levonorgestrel-releasing Intrauterine System was placed into the patient utero,the menstrual flow,dysmenorrhea of the degree,uterine size change were observed and analysed before and after treatment.Result:Before treatment the dysmenorrhea score,menstrual flow,CA125,uterine size were (84.12±4.90)points,(212.01±53.01)ml,(70.38±68.50)U/ml,(190.16±90.04)cm3,placed 3 months in patients with dysmenorrhea score,menstrual flow,CA125,respectively (21.50±8.11)points,(48.21±14.88)ml,(26.01±25.42)U/ml,the difference were statistically significant(P<0.05).Place six months after uterine size was (170.56±75.50)cm3,and the difference was not statistically significant than placed before(P>0.05).In addition,patients had no significant adverse reactions.Conclusion:The effect of Levonorgestrel-releasing Intrauterine System in the treatment of adenomyosis is obvious,this method can effectively improve patient menstrual flow,dysmenorrhea and other symptoms,and safe,reliable,it is worthy of clinical application.%目的:观察左炔诺孕酮宫内缓释系统治疗子宫腺肌症的临床疗效。方法:选取2012年1月-2013年3月笔者所在医院收治的40例子宫腺肌症患者为研究对象,将左炔诺孕酮宫内缓释系统放置到患者宫内,对放置前后患者月经量、痛经程度、子宫大小变化等进行全面的观察和分析。结果:放置前患者痛经评分、月经量、CA125、子宫大小分别为(84.12±4.90)分、(212.01±53.01)ml、(70.38±68.50)U/ml、(190.16±90.04)cm3,放置后3个月患者痛经评分、月经量、CA125分别为(21.50±8.11)分、(48.21±14.88)ml、(26.01±25.42)U/ml,差异有统计学意义(P<0.05)。放置6个月后子宫大小为(170.56±75.50)cm3,与放置前比较差异无统计学意义(P>0.05)。此外,患者均无出现明显不良反应。结论:左炔诺孕酮宫内缓释系统治疗子宫腺肌症效果明显,能有效改善患者月经量、痛经等症状,且安全可靠,值得在临床上推广应用。

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