Objective:To investigate the occurrence of the coagulation phenomenon and preventive coagulation phenomenon in the heparin-free dialysis.Method:40 cases of acute renal failure or chronic renal failure which were prone to bleeding tendency in high-risk were selected.40 cases taken modified heparin-free dialysis,the dialyzer coagulation in each dialysis was observed.Result:40 patients at high risk of bleeding associated with acute renal failure,chronic renal failure taken heparin-free hemodialysis.They were no aggravating bleeding,also had not appeared the extracorporeal circulation of blood coagulation,but vein on the pot wall had a little blood,a blood coagulation phenomenon did not occur.Conclusion:Acute renal failure,chronic renal failure patients with high risk of bleeding treatment effect are significantly in the heparin-free hemodialysis,and high safety,no increased bleeding.It is no clotting function,can effectively improve the patient's survival rate and improve the prognosis of the quality of life.%目的:探讨无肝素透析中如何及时发现凝血先兆及预防凝血现象的发生.方法:选择有高危出血倾向的急、慢性肾功能衰竭患者40例,应用改良无肝素血液透析40例次,观察每例次透析时透析器的凝血情况.结果:40例急、慢性肾功能衰竭,合并高危出血患者进行无肝素血透,均未见出血加重,也未出现体外循环血液凝固,但静脉壶壁上有少许凝血,未发生一次血液凝固现象.结论:采用无肝素透析对有高危出血倾向的急、慢性肾功能衰竭患者治疗效果显著且安全性高,无出血加重,未出现凝血情况,可有效的提高患者的生存率、改善其预后的生活质量.
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