136例婴幼儿泪囊炎病原菌分布及耐药性分析

摘要

Objective:To analyze the distribution and drug resistance of infant dacryocystitis pathogens so that to provide reference for clinical the use of antimicrobial agent.Method:Selected from January 2013 to May 2014 in our hospital eye clinic patients diagnosed with a total of 136 cases of infant dacryocystitis, squeeze the pus sac Ministry reflux as specimens sent for bacterial culture and drug susceptibility analysis.Result:A total of 113 specimens were culture-positive which detected in 113 strains of pathogens,detection rate was 83.1%,Gram-negative bacilli was dominant,but the highest detection rate pathogen was Staphylococcus aureus(17 cases,15.0%),three for MRSA strains,followed by Staphylococcus epidermidis(13 cases,11.5%),three for MRCoNS strains.Not detected fungi.Susceptibility,all strains were highly resistant to penicillin,but resistance to aminoglycosides and fluoroquinolones lower rates.Conclusion:Infant dacryocystitis pathogen distributed mainly with Staphylococcus aureus,Staphylococcus epidermidis,Haemophilus influenzae,Neisseria based.Most strains have a lower resistant rate to aminoglycosides and fluoroquinolones and high rate to penicillin-resistant.%目的：分析婴幼儿泪囊炎的致病菌分布和耐药性，指导临床合理用药。方法：选取2013年1月-2014年5月笔者所在医院眼科门诊诊断为婴幼儿泪囊炎的患儿共136例，挤压泪囊部反流的脓汁作为标本送检，进行细菌培养及药物敏感性分析。结果：136份标本，113份培养阳性，共检出113株病原菌，检出率83.1%，以革兰阴性杆菌为主，但检出率最高的病原菌为金黄色葡萄球菌(17株，15.0%)，MRSA菌株3株，其次为表皮葡萄球菌(13株，11.5%)，MRCoNS菌株3株；未检出真菌。药敏方面，所有菌种对青霉素类耐药率较高，而对氨基糖苷类和喹诺酮类耐药率较低。结论：婴幼儿泪囊炎病原菌以金黄色葡萄球菌、表皮葡萄球菌、流感嗜血杆菌、奈瑟氏菌属为主；大多数菌株对氨基糖苷类和喹诺酮类耐药率较低，对青霉素类耐药率较高。